Leppert Foundation
Dr. Phyllis Leppert, MD, PhD, and Dr. Friederike Jayes, PhD, DVM, of Duke University

The Leppert Foundation has three main goals:

1) To provide peer-reviewed grants to research universities and allocated to qualified scientists through the Campion Fund

Topics for each year will be selected jointly by the Board of Directors and the Scientific Advisory Board. The topic will be announced in April and grant proposals will be accepted through October. We will also give two awards to the best presentations given by junior investigators at each annual meeting of the Triangle Consortium for Reproductive Biology (TCRB) on March 8th, 2014.  These awards will be given to the investigator’s institutions to be allocated to them.

2) To host an annual conference for the scientific community

“Mechanotransduction in the Reproductive Tract” is the topic for our next conference, October 14–15, 2014, at the Washington Duke Inn, Durham, North Carolina. Plenary Speakers will be: Rocky Tuan, University of Pittsburgh; James H. Segars, NICHD; Janice Evans, Johns Hopkins; Stephen Lye, University of Toronto; and Farshid Guilak, Duke University. Registration will open in April 2014. Abstract submission deadline is August 15, 2014. The proceedings of this meeting will be published.

3) To provide education regarding fertility research to the public

In addition to the research and articles published here, information is available through our blog, VDRs, and through our Lunch and Learn series.  For more information, please contact us.

Areas of Translational Research

  • uterine fibroids
  • endometriosis
  • adnenomyosis
  • polycystic ovarian syndrome
  • Peyronie’s Disease
  • benign prostatic hypertrophy
  • varicocele
  • other causes of male and female infertility
  • inherited genetic disease

Areas of Basic Research

  • gene expression and epigenetics
  • organogenesis of the reproductive tracts
  • steroid hormone regulation
  • neuroendocrinology
  • gametogenesis
  • growth and apoptosis in reproductive tissue
  • ligands and receptors
  • mechanotransduction


The Phyllis and Mark Leppert Foundation for Fertility Research, a 501 (c ) (3) public charity, was founded to promote basic biomedical research on diseases that affect the human reproductive system.  The Campion Fund is funded through tax-deductible donations to the Foundation.


Focus 2014-2015

Stop the Pain and Bleeding:  Fund Fibroid Research

Uterine Fibroids

Uterine fibroids are firm, stiff nodular tumors that occur in women’s childbearing years.

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The cost of uterine fibroids to our health care system is extremely high and is thought to be $5.9 to 34 billion annually.  Amazingly this is more than the current cost to treat Type II Diabetes in this country.

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Symptoms include heavy periods and heavy bleeding between periods leading in many women to anemia.

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Some uterine fibroids lead to infertility.

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Studies show that fibroids grow differently in African-American women compared to White women.  It is estimated that 80% of African-American women and 70% of Caucasian women will develop uterine fibroids before age 50.

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In analyses examining both number and size of fibroids, 34% of African-American women versus 7.6% of White women had 10 or more fibroids and at least one large fibroid of 5 cm or more.

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Hysterectomy is still the definite treatment for symptomatic fibroids and because it ends the ability to have a child it is a tragedy for many young women.

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Treatment options will be stagnant until scientists discover the underlying reason for uterine fibroid growth and development.

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This is why The Campion Fund has chosen to focus on fibroids in 2014-2015.  Please help us support basic research and make new treatments a reality.

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Phyllis C. Leppert, MD, PhD, Durham, NC
Mark F. Leppert, PhD, Salt Lake City, UT
Tami Leppert, PhD, Salt Lake City, UT

Sarah Berga, MD, Winston-Salem, NC
Nancy Kellett, RN, MPH, Salisbury, CT
James H. Segars, MD, Bethesda, MD
Hugh Taylor, MD, New Haven, CT
Humphrey Yao, PhD, Research Triangle Park, NC

Lisa Jones, Evansville, IN
William Kellett, Salisbury, CT
Gary Leppert, Columbus, OH


Susan Allender, Durham, NC
Haywood Brown, Durham, NC
Phillip Cato, Potomac, MD
Kathryn Daily, Durham, NC
John Daily, Durham NC,
Louane Frey, Cary, NC
William Hackney, Pittsboro, NC
Friederike Jayse, Cary, NC
Kathyrn McClelland, RTP , NC
Lisa Muasher, Chapel Hill, NC
Suheil Muasher, Chapel Hill, NC
David Schomberg, Hillsboro, NC
Darlene Taylor, Burlington, NC
Michelle Wolff, Durham, NC


The Campion Fund 990 Form can be found here.

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